Rodents and aquatic organisms are used to research for the toxicity of Phthalic Acid Esters(PAEs). As to aquatic organisms, there are six Phthalic Acid Esters(DMP, DEP, DAP, DBP, DIBP, BBP) in the experiment,and it found out that the higher molecular weight of Phthalic Acid Esters do not produce acute or chronic toxicity to aquatic organisms, and low molecular weight on the toxicity of Phthalic Acid Esters do. The common methods of degradation of Phthalic Acid Esters at present is Microbial degradation, Fungal biodegradation, Sonochemical degradation and Photocatalytic degradation. It summarized and points out its advantages and problems. Finally, it has made expectation for the future development direction.