依那普利
依那普利
医学
血管紧张素转换酶
活性代谢物
马来酸依那普利
血管紧张素转换酶抑制剂
药理学
酶抑制剂
心力衰竭
肽基二肽酶A
代谢物
血管紧张素II
酶
内科学
药代动力学
血压
生物化学
化学
作者
Brunner Hr,J. Nussberger,B. Waeber
出处
期刊:PubMed
日期:1986-01-01
卷期号:41 (5): 341-50
摘要
Enalapril is a new angiotensin converting enzyme inhibitor which, when absorbed by the digestive tract, is converted to enalaprilat. This metabolite is, in fact, the active form of enalapril. Its duration of action is sufficiently long so that enalapril can be administered in a single daily dose. Enalapril has been proved to be a highly effective therapeutic agent which is well tolerated by patients with arterial hypertension or severe congestive heart failure.
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