Clinical Analysis of the Short-term Efficacy and Toxicity of the Advanced Gastric Cancer Treated with ELFP Regimen and EFP Regimen

Objective To evaluate the efficacy and toxicity of ELFP and EFP regimen in the treatment of advanced gastric cancer.Method 63 patients treated with ELFP regimen were equally divided into three groups [the low-dose CF (leucovorin) group, the median-dose CF group and the high-dose CF group];21 patients were treated with EFP regimen. Results Response rates were 65.1% (41/63) and 42.9%(9/21),respectively for these two regimens. Besides, response rates were 61.9%(13/21), 66.6%(14/21) and 66.6%(14/21),separataly for these three gruops in ELFP regimen. There was notable statistical difference between ELFP regimen and EFP regimen, but no statstical difference among these three groups.Conclusion ELFP regimen is regarded as a better regimen for advanved gastric cancer.