医学
内科学
代谢综合征
急性冠脉综合征
荟萃分析
优势比
危险系数
置信区间
心肌梗塞
糖尿病
血压
心脏病学
作者
Yong Yang,Haili Shen,Zhigeng Jin,Dongxing Ma,Qing Zhao,Xuyi Zhang
出处
期刊:Hormone and Metabolic Research
[Georg Thieme Verlag KG]
日期:2021-03-10
卷期号:53 (04): 257-263
摘要
The association between metabolic syndrome (MetS) and survival outcome after acute coronary syndrome (ACS) remains controversial. This meta-analysis sought to examine the association of MetS with all-cause mortality among patients with ACS. Two authors independently searched PubMed and Embase databases (from their inception to June 27, 2020) for studies that examined the association of MetS with all-cause mortality among patients with ACS. Outcome measures were in-hospital mortality and all-cause mortality during the follow-up. A total of 10 studies involving 49 896 ACS patients were identified. Meta-analysis indicated that presence of MetS was associated with an increased risk of long-term all-cause mortality [risk ratio (RR) 1.25; 95% CI 1.15-1.36; n=9 studies] and in-hospital mortality (RR 2.35; 95% CI 1.40-3.95; n=2 studies), respectively. Sensitivity and subgroup analysis demonstrated the credibility of the value of MetS in predicting long-term all-cause mortality. MetS is associated with an increased risk of long-term all-cause mortality among patients with ACS. However, additional studies are required to investigate the association of MetS with in-hospital mortality.
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