急性肾损伤
肾
医学
碳水化合物代谢
肾葡萄糖重吸收
葡萄糖稳态
平衡
重吸收
肾脏疾病
新陈代谢
内科学
内分泌学
生物信息学
生物
糖尿病
2型糖尿病
胰岛素抵抗
作者
Lu Wen,Ying Li,Siyao Li,Xiaoru Hu,Qingqing Wei,Zheng Dong
标识
DOI:10.3389/fmed.2021.744122
摘要
glucose reabsorption, production, and utilization. Conversely, aberrant glucose metabolism is involved in the onset, progression, and prognosis of kidney diseases, including acute kidney injury (AKI). In this review, we describe the regulation of glucose homeostasis and related molecular factors in kidneys under normal physiological conditions. Furthermore, we summarize recent investigations about the relationship between glucose metabolism and different types of AKI. We also analyze the involvement of glucose metabolism in kidney repair after injury, including renal fibrosis. Further research on glucose metabolism in kidney injury and repair may lead to the identification of novel therapeutic targets for the prevention and treatment of kidney diseases.
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