Since the discovery that chlorofluorocarbons (CFCs) destroy the ozone layer, the need to reduce the release of these refrigerants into the environment has become critical. A total ban of ozone-depleting CFCs is expected within a few years, and hydrofluorocarbons (HFCs) and fluorocarbons (FCs) and their mixtures are expected to be used during a transition period. Several HFC and FC refrigerants are currently being considered as CFC substitutes. The electronic refrigerant leak detectors currently being considered as CFC substitutes. The electronic refrigerant leak detectors currently on the market were developed to detect CFCs and are not as sensitive to HFCs. Although incremental improvement can be made to these devices to detect HFCs, they often lead to increased false signals. Also, there is no simple device available to measure the composition of a refrigerant mixture. The authors present two new concepts to aid in the development of two portable instruments that can be used for HFC leak detection and for quantitative measurement of refrigerant mixture compositions. The development of simple, easy-to-use portable leak detectors and refrigerant mixture meters is essential to the wide use of alternative refrigerants in industry.