对映选择合成
立体中心
化学
齿合度
表面改性
配体(生物化学)
组合化学
立体化学
催化作用
作者
Pu-Fan Qian,Jun-Yi Li,Tao Zhou,Bing-Feng Shi
出处
期刊:Synthesis
[Georg Thieme Verlag KG]
日期:2022-03-18
摘要
Transition metal-catalyzed enantioselective C−H functionalization has emerged as an efficient and powerful strategy to access various chiral molecules. Recently, this strategy also provided a complementary pathway to the construction of P- and S-stereogenic compounds. In this short review, we summarize the development and applications of various catalytic systems, including Pd(II)/MPAA, Pd(0)/trivalent phosphorus chiral ligand, chiral CpxM(III) (M = Rh, Ir), half-sandwich d6 Ir(III) and Ru(II) with chiral carboxylic acid (CCA) ligand, Ir(I)/chiral bidentate boryl ligand, and Ir(I)/chiral cation, in the access of these chiral compounds via enantioselective C−H functionalization.
科研通智能强力驱动
Strongly Powered by AbleSci AI