Development of psoriasis during treatment with dupilumab: A systematic review

To the Editor: Postapproval reports of new or worsening psoriasis developing in patients while on dupilumab treatment have been increasing. To our knowledge, we performed the first systematic review characterizing all such cases. Embase, PubMed, and Web of Science databases were queried using the title search term "dupilumab" to identify all published literature through April 3, 2021. Two reviewers independently performed screening and data extraction (CMB and MHP). During title and abstract screening, all English language primary literature was included for a full-text review.