医学
心脏病学
内科学
射血分数
感染性休克
心室功能
作者
Daniel B. Knox,Michael J. Lanspa,Emily L. Wilson,Benjamin Haaland,Sarah J. Beesley,Eliotte L. Hirshberg,Theodore P. Abraham,Saraschandra Vallabhajosyula,Colin K. Grissom,Stavros G. Drakos,Samuel M. Brown
标识
DOI:10.1177/08850666211053796
摘要
Septic shock is a common deadly disease often associated with cardiovascular dysfunction. Left ventricular longitudinal strain (LV LS) has been proposed as a sensitive marker to measure cardiovascular function; however, it is not available universally in standard clinical echocardiograms. We sought to derive a predictive model for LV LS, using machine learning techniques with the hope that we may uncover surrogates for LV LS. We found that left ventricular ejection fraction, tricuspid annular plane systolic excursion, sepsis source, height, mitral valve Tei index, LV systolic dimension, aortic valve ejection time, and peak acceleration rate were all predictive of LV LS in this initial exploratory model. Future modeling work may uncover combinations of these variables which may be powerful surrogates for LV LS and cardiovascular function.
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