发育不良
印戒细胞癌
微卫星不稳定性
癌症
医学
腺癌
病理
癌
内科学
生物
基因
微卫星
生物化学
等位基因
出处
期刊:Pathologe
[Springer Nature]
日期:2021-11-22
卷期号:43 (1): 8-15
被引量:17
标识
DOI:10.1007/s00292-021-01023-7
摘要
The fifth edition of the World Health Organization (WHO) classification of digestive system tumours was published in 2019. The classification of invasive carcinoma is basically the same as in the fourth edition, but the description of each histological type has been updated, and some rare subtypes such as micropapillary carcinoma, gastric adenocarcinoma of the fundic gland type and undifferentiated carcinoma have been added and explained. Although this classification did not provide specific numerical criteria for the diagnosis of signet-ring cell carcinoma in poorly cohesive carcinoma, an additional study defined signet-ring cell carcinoma as having more than 90% signet-ring cells. The molecular classification of gastric cancer (Epstein-Barr virus-positive type, microsatellite instability type, genomically stable type, chromosomally unstable type) was additionally introduced. Many pages in the present classification have been devoted to precancerous lesions, and this article focuses on foveolar-type adenoma/dysplasia.
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