焦磷酸异戊烯酯
转移酶
生物合成
萜烯
甲基转移酶
萜类
ATP合酶
化学
立体化学
异构酶
生物化学
酶
焦磷酸法尼酯
法尼基二磷酸合酶
基因
甲基化
作者
Birgit Piechulla,Nancy Magnus,Marie Chantal Lemfack,Stephan H. von Reuß
标识
DOI:10.1016/j.trechm.2020.01.006
摘要
Serratia plymuthica 4Rx13 emits the unique hydrocarbon sodorifen (C16H26) in which every carbon of the bicyclo[3.2.1]octane skeleton carries a methyl unit. Biosynthesis of this homosesquiterpene depends on a gene cluster comprising four genes, an isopentenyl pyrophosphate (PP) isomerase, a deoxyxylulose-5-phosphate synthase, a methyltransferase (MT), and a terpene synthase. The latter two enzymes are required and sufficient for the noncanonical biosynthesis of sodorifen.
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