The applications and future of emerging biomarkers in the precision diagnosis and treatment of inflammatory bowel disease

Inflammatory bowel disease is chronic intestinal inflammatory disease with unknown etiology, which may be associated with environmental, genetic and immune factors. The personalized or accurate diagnosis and treatment are a new development trend for IBD clinical management. The detection of biomarkers is very important in the diagnosis, treatment and clinical management of IBD. In addition to the traditional biomarkers, the emerging new markers based on genetics, epigenetics, microbial and metabolomics have also shown better future applications in several areas, such as the applications of biomarkers in diagnosis and differential diagnosis of IBD. The determination of disease activity, severity and complications. The selection for treatments in IBD and prediction of therapeutic effects. These biomarkers will also contribute to personalized clinical management of IBD.(Chin J Lab Med, 2018, 41: 703-707) Key words: Inflammatory bowel diseases; Biomarkers; Precision medicine