自愈水凝胶
硼砂
材料科学
瓜尔胶
银纳米粒子
环境扫描电子显微镜
热重分析
生物材料
纳米颗粒
核化学
抗菌活性
化学工程
复合材料
纳米技术
扫描电子显微镜
高分子化学
化学
细菌
有机化学
工程类
原材料
生物
生物化学
遗传学
作者
Chanon Talodthaisong,Wissuta Boonta,Saengrawee Thammawithan,Rina Patramanon,Nuntaporn Kamonsutthipaijit,James A. Hutchison,Sirinan Kulchat
标识
DOI:10.1016/j.mtcomm.2020.100992
摘要
Biomaterial-based hydrogels incorporating antibacterial agents may provide sustainable solutions to biomedical device failures and the prevention of infections. Herein we report guar gum hydrogels, cross-linked with borax and loaded with silver nanoparticles, that are injectable, exhibit rapid self-healing, and show antibacterial properties towards both gram-positive and gram-negative bacteria. The hydrogels are fully characterized by infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy, and rheological measurements. An important focus was to minimize borax content, thus reducing the toxicity of the gels greatly, whilst retaining their favorable viscoelastic properties. When the low borax-content hydrogels are composited with curcumin-stabilized silver nanoparticles, the hydrogels show activity against Escherichia coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa), and Staphylococcus aureus (S. aureus).
科研通智能强力驱动
Strongly Powered by AbleSci AI