Nematicidal Metabolites Produced by the Endophytic Fungus Geotrichum sp. AL4

Abstract From the endophytic fungal strain Geotrichum sp. AL4, cultivated from the leaves of the neem tree ( Azadirachta indica ), four compounds, 1 – 4 , were isolated from the AcOEt extract, including two new, chlorinated, epimeric 1,3‐oxazinane derivatives. All compounds were assessed for their nematicidal activities against the nematodes Bursaphelenchus xylophilus and Panagrellus redivivus , and three out of the four isolates showed noticeable bioactivities.