What Determines Nutritional Recovery in Malnourished Children After Correction of Congenital Heart Defects?

医学 营养不良 人体测量学 儿科 标准分 逻辑回归 内科学 计算机科学 机器学习
作者
Balu Vaidyanathan,Reshma Radhakrishnan,Deepa Aravindakshan Sarala,K. R. Sundaram,Raman Krishna Kumar
出处
期刊:Pediatrics [American Academy of Pediatrics]
卷期号:124 (2): e294-e299 被引量:59
标识
DOI:10.1542/peds.2009-0141
摘要

Malnutrition is common in children with congenital heart disease (CHD), especially in developing countries.To examine the impact of corrective intervention on the nutritional status of children with CHD and identify factors associated with suboptimal recovery.Consecutive patients with CHD in a tertiary center in South India were evaluated for nutritional status before and 2 years after corrective intervention. Anthropometry was performed at presentation and every 6 months for 2 years, and z scores were compared. Malnutrition was defined as a weight-for-age, height-for-age, and weight/height z score <-2. Determinants of malnutrition were entered into a multivariate logistic regression analysis model.Of 476 patients undergoing corrective intervention (surgical: 344; catheter-based: 132) z scores of less than -2 for weight for age, height for age, and weight/height were recorded in 59%, 26.3%, and 55.9% of patients, respectively, at presentation. On follow-up (425 patients [92.5% of survivors; 20.63 +/- 13.1 months of age]), z scores for weight for age and weight/height improved significantly from the baseline (weight: -1.42 +/- 1.03 vs -2.19 +/- 1.16; P < .001; weight/height: -1.15 +/- 1.25 vs -2.09 +/- 1.3; P < .001). Height-for-age z scores were not significantly different. Malnutrition persisted in 116 (27.3%) patients on follow-up and was associated with a birth weight of
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