催化作用
过氧化氢
单线态氧
化学
清除
过氧化氢酶
超氧化物
铂纳米粒子
铂金
纳米颗粒
超氧化物歧化酶
分解
光化学
活性氧
氧气
组合化学
无机化学
有机化学
纳米技术
抗氧化剂
酶
材料科学
生物化学
作者
Yi Liu,Haohao Wu,Meng Li,Jun‐Jie Yin,Zhihong Nie
出处
期刊:Nanoscale
[The Royal Society of Chemistry]
日期:2014-08-13
卷期号:6 (20): 11904-11910
被引量:171
摘要
Recently, platinum (Pt) nanoparticles (NPs) have received increasing attention in the field of catalysis and medicine due to their excellent catalytic activity. To rationally design Pt NPs for these applications, it is crucial to understand the mechanisms underlying their catalytic and biological activities. This article describes a systematic study on the Pt NP-catalyzed decomposition of hydrogen peroxide (H2O2) and scavenging of superoxide (O2˙−) and singlet oxygen (1O2) over a physiologically relevant pH range of 1.12–10.96. We demonstrated that the catalytic activities of Pt NPs can be modulated by the pH value of the environment. Our results suggest that Pt NPs possess peroxidase-like activity of decomposing H2O2 into ˙OH under acidic conditions, but catalase-like activity of producing H2O and O2 under neutral and alkaline conditions. In addition, Pt NPs exhibit significant superoxide dismutase-like activity of scavenging O2˙− under neutral conditions, but not under acidic conditions. The 1O2 scavenging ability of Pt NPs increases with the increase in the pH of the environment. The study will provide useful guidance for designing Pt NPs with desired catalytic and biological properties.
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