Progress of commercial neonicotinoid insecticide such as imidacloprid,thiamethoxam,clothianidin and acetamiprid,in seed treatment including product registered,crops protected and targets,and control effect were reviewed in this paper.Neonicotinoid insecticide in seed treatment had some problems in our country at present,such as fewer neonicotinoid insecticides applied as seed treatment agents,good film former deficiency in our country and some pests resistance to neonicotinoid insecticides.And the further development of neonicotinoid insecticide in seed treatment was put forward.