OBJECTIVE To observe the efficacy of levofloxacin in treatment of community-acquired pneumonia both in the adminstration of intravenous drip and orl sequential therapy.METHODS 81 patients with community-acquired pneumonia,first in treatment with levofloxacin 0.2g each time,iv.gtt,bid;when the symptoms improved,then divided into two groups:the treatment group and controlled group.48 cases in treatment group,were switched levofloxacin 0.1g each,o.p,bid,course was 4~7d;the other 33 cases were cotrolled group,the original theapic method was continued,and course was 3~6d.RESULTS The efficacy of the two groups have no significant differences(P0.05),CONCLUSION Levofloxacin in both adminstration of intravenous drip and oral sequential therapy to therapy community-acquired pneumonia were as effectively as intravenous drip allover the course.