Objective:To analyze the pathogenesis and correlative factors of acute upper gastrointestinal hemorrhage.Methods:90 cases with acute upper gastrointestinal hemorrhage from Jan 2010 to Jun 2012 in our hospital were selected as the research objectives.The pathogenesis,predisposition and correlative factors were analyzed using the statistical method.Results:HG,DU,GU were the main pathogenesis of acute upper gastrointestinal hemorrhage.Different pathogeneses had different predispositions(P0.01).Pathogenesis distribution in Youth group,middle-aged group,and older age-group were different(P0.01).Pathogenesis distribute in male and female had no significant difference(P0.05).Conclusions:There are lots of Pathogeneses of acute upper gastrointestinal hemorrhage,and pathogenesis distribution in different age classes is different.