Wireless shape memory polymer microactuator for implantable drug delivery aplication

A wireless shape-memory-polymer - based implantable drug-delivery device operated by external radio frequency magnetic fields is designed and fabricated. The shape-memory-polymer actuator is driven by a wireless resonant heater which is bonded directly to it activated only when the field frequency is tuned to the resonant frequency of the heater. The device is operated using radiofrequency power of 0.05 W. Experiments are conducted to demonstrate the application of the developed implantable drug-delivery device using food coloring and acidic solution loaded in the device reservoir. The device is successfully operated in DI water through wireless activation and acidic solution stored in the reservoir is released and diffused in water with average release rate of 0.172 μL/min.