PCR210 Quality of Life and Productivity Losses of Dysmenorrhea Patients in Korea

Dysmenorrhea is a common symptom in women. Dysmenorrhea impairs patients’ quality of life and causes productivity loss in patients. However, there is a limited study on the disease burden of dysmenorrhea. This study was conducted to measure health-related quality of life and productivity loss of dysmenorrhea patients in Korea. Secondary analysis with the data of a multicenter, randomized controlled trial evaluating efficacy, safety, and economic effect of Dangguijagyak-san on primary dysmenorrhea patients was performed. 16-40 years old women who had primary dysmenorrhea for three consecutive months with at least 50 VAS scores were included in the trial. We descriptively analyzed the health-related quality of life and productivity loss of the patients. Subgroup analysis was conducted by five-year age groups. EuroQol-5D (EQ-5D), Verbal multidimensional scoring system (VMSS), Retrospective symptom scale (RSS), and Short form McGill pain questionnaire (SF-MPQ) were used to measure patients’ quality of life. iMTA productivity cost questionnaire (iPCQ) was used to estimate patients’ productivity loss due to dysmenorrhea. A total of 240 dysmenorrhea patients were included in the analysis. The mean EQ-5D score was 0.5702. The average VMSS grade was 2 (“daily activity is affected; analgesics required and give sufficient relief so that absence from school is unusual; moderate pain”). RSS results showed during one menstruation cycle, patients slept 4.24 hours more than usual because of dysmenorrhea, and 57.5% of total patients took an average of 3.52 analgesics to relieve pain. The mean productivity loss due to absenteeism, presenteeism, and unpaid work was $11.40, $151.53, and $58.91, respectively. Total productivity loss due to dysmenorrhea was $ 221.85 per month. This study provides an overview of dysmenorrhea women’s health-related quality of life in Korea by presenting measurement results of various health-related quality of life instruments. Also, this study provides information on productivity loss due to dysmenorrhea in Korean patients.