Optimisation of natural neolignan as pesticide candidates: semisynthesis and insecticidal potential of honokiol derivatives bearing dual phenyl-urea/-thiourea moieties

values of 0.15, 0.19, and 0.22 mg/mL, respectively, exceeding those of toosendanin and rotenone. Accordingly, these potent compounds hold potential as novel agrochemicals for crop protection.