Adverse effects of topical tacrolimus compounded ophthalmic preparations

The main aim of this review is to provide an overview of the key ocular side effects associated with topical tacrolimus compounded ophthalmic preparations Materials and methods: Review of literature using Pubmed database. The use of topical tacrolimus may be associated with side effects ranging from mild ocular discomfort to more server complications like loss of integrity of corneal surface, corneal ulcer and infectious keratitis. However, the use of topical tacrolimus is not associated with increased incidence of secondary glaucoma or cataract. It is imperative to understand the potential side effects associated with topical tacrolimus ophthalmic preparations to optimize the treatment outcomes and guarantee patient safety. Routine ophthalmic examinations should be conducted to detect these side effects early and address them appropriately.