Facile Gram-Scale Production of Cu/Cu 2 O Core/Shell Nanoparticles Densely Embedded in a Porous Carbon Framework for Cost-Effective Peroxidase Mimicking

O NPs around 15 nm in size can be obtained at temperatures below 600 °C. Importantly, they can be used directly without purification, significantly reducing production costs compared to natural enzymes. The sample obtained at 300 °C, exhibiting the highest Cu(I) content, displays optimal POD-like activity and was further demonstrated in the detection of glutathione and glucose. This study is anticipated to guide the future development of scalable and cost-effective POD nanozymes for practical applications.