主动脉夹层
医学
膨胀(度量空间)
升主动脉
主动脉瘤
动脉瘤
主动脉
内科学
心脏病学
外科
数学
组合数学
作者
Lianjie Sun,Haoyou Li,Xing Feng,Li Xiao,Guoqing Wang,Jianchao Sun,Xiaoming Zhang,Wenfeng Zhang,Jianxun Wang,Zhaozhuo Niu,Gaoli Liu
标识
DOI:10.1093/ejcts/ezae016
摘要
This study aimed to analyze and determine the role of aortic length and curvature in the pathogenesis of acute type-A aortic dissection (ATAAD) with ascending aortic diameters (AADs) <5 cm.We reviewed the clinical and imaging data of patients with ATAAD (n = 201) and ascending aortic dilation (n = 83). Thoracic aortic bending index (TABI) was used to quantify aortic curvature and analyze its role in ATAAD below the diameter risk threshold.The AAD was <5.0 cm and <4.0 cm in 78% and 37% of patients with ATAAD, respectively. The median ascending aortic length (AAL) was 104.6 mm (Q1-Q3, 96.5-113.6 mm), and in 62.7% of patients, it was <11 cm. The median TABI was 14.99 mm/cm (Q1-Q3, 14.18-15.86 mm/cm). Patients with ATAAD and those with aortic dilation were matched for AAD, age, sex, height, and other clinical factors. After matched, the dissection group had higher AALs (median, 102.9 mm; Q1-Q3, 96.0-112.5 mm vs median, 88.2 mm; Q1-Q3, 83.7-95.9 mm; p < 0.001) and TABI (median, 14.84 mm/cm; Q1-Q3, 14.06-15.83 mm/cm vs median, 13.55 mm/cm; Q1-Q3, 13.03-14.28 mm/cm; p < 0.001). According to the regression analysis, the area under the curve required to distinguish patients with ATAAD from those with aortic dilation was 0.831 in AAL, 0.837 in TABI, and 0.907 when AAL was combined with TABI.The patients with ATAAD had higher AAL and TABI than with aortic dilation. The combination of TABI and AAL might be a potential morphological marker for determining ATAAD risk below the current aortic diameter risk threshold.
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