药物发现
药品
鉴定(生物学)
计算生物学
药物代谢
药物开发
个性化医疗
生物信息学
药理学
数据科学
计算机科学
医学
生物
植物
作者
Dogfounianalo Somda,Stephen Wilson Kpordze,Mercy Jerpkorir,Mishell Chantelle Mahora,Jecinta Ndung’u,Sally Wambui Kamau,V Arthur,Amel Elbasyouni
出处
期刊:IntechOpen eBooks
[IntechOpen]
日期:2023-11-29
被引量:4
标识
DOI:10.5772/intechopen.113712
摘要
Bioinformatics plays a crucial role in various aspects of drug discovery, drug metabolism, and pharmacology. In drug discovery, bioinformatics enables the efficient analysis and interpretation of large-scale biological data, facilitating target identification, lead compound optimization, and prediction of drug-target interactions. It aids in the identification and characterization of potential drug targets through genomic and proteomic analyses. Additionally, bioinformatics assists in the prediction of drug metabolism and pharmacokinetic properties, offering insights into the safety and efficacy of potential drug candidates. Furthermore, it contributes to pharmacology by enabling the analysis of drug-drug interactions, adverse drug reactions, and personalized medicine approaches. The integration of computational tools and algorithms with biological and chemical data has accelerated the drug discovery process, improved success rates, and reduced costs. Bioinformatics has become an indispensable tool in the development of novel therapeutics and the optimization of drug efficacy and safety. This book chapter elucidates the profound impact of bioinformatics in drug metabolism and pharmacology, emphasizing the transformative potential it holds for the future of pharmaceutical research, ultimately improving patient outcomes and bringing innovative therapies.
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