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Three years’ interventional neurology experience in Turkey with the Thrombite thrombectomy device in large vessel occlusion in the anterior circulation: safety, efficacy, and clinical outcome

医学 四分位间距 溶栓 改良兰金量表 冲程(发动机) 神经组阅片室 腹股沟 闭塞 神经学 神经血管束 脑梗塞 外科 人口 介入放射学 栓塞 回顾性队列研究 内科学 缺血性中风 心肌梗塞 缺血 精神科 机械工程 环境卫生 工程类
作者
Çetin Kürşad Akpınar,Erdem Gürkaş,Atilla Özcan Özdemi̇r,Hasan Doğan,Ayşenur Önalan,Serhan Yıldırım,Zülfikar Memiş,Emrah Aytaç,Bilgehan Atılgan Acar,Muhammed Nur Öğün,Özlem Aykaç,Zehra Uysal Kocabaş,Türkan Acar,H A Eryılmaz,Berkhan Topaktaş
出处
期刊:Frontiers in Neurology [Frontiers Media]
卷期号:15
标识
DOI:10.3389/fneur.2024.1320510
摘要

Introduction While the Thrombite device differs from the Solitare stent with its Helical open-side structure feature, it shows great similarity with its other features. We assessed the Thrombite device’s effectiveness and safety in this study. Materials and methods The study was a retrospective analysis of patients who were included in the Turkish Interventional Neurology database and who had mechanical thrombectomy with the Thrombite device as the first choice between January 2020 and January 2023. The type of study is descriptive research. Result Using the Thrombite thrombectomy device, 525 patients received treatment. The median baseline National Institutes of Health Stroke Scale (NIHSS) score was 13, the median initial Alberta Stroke Program Early Computed Tomography (ASPECT) score was 8, and the mean patient age was 68.6+11.7 years. Between the groin puncture and the successful recanalization, the median time was 34 minutes (interquartile range [IQR]: 15–45). 48.2% (modified treatment in cerebral infarction; mTICI) 2b/3% and 33.9% (mTICI 2c/3) were the first-pass recanalization rates. In the end, 87.7% of patients had effective recanalization (thrombolysis in cerebral infarction 2b/3). In the “first-pass” subgroup, the favorable functional result (modified Rankin Scale 0–2) was 51.8%, while it was 41.6% for the entire patient population. The rate of embolization into new territory/different territory were 2.1/0.1%. 23 patients (4.5%) had symptomatic hemorrhage. Conclusion The Thrombite device showed a good safety profile and high overall successful recanalization rates in our experience.
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