The biceps femoris short head (BiFeS) block is a novel, ultrasound-guided, motor-sparing regional anesthesia technique targeting the posterolateral sensory innervation of the knee. We present two unilateral total knee arthroplasty (TKA) cases in which BiFeS was combined with adductor canal block (ACB) under spinal anesthesia. Blocks were administered postoperatively, before the onset of pain. Both patients had low pain scores, preserved quadriceps and ankle motor function, minimal morphine consumption (6 mg and 5 mg), and high Quality of Recovery-15 (QoR-15) scores (140 and 137). BiFeS may be a valuable adjunct to ACB for multimodal analgesia in TKA.