伤口愈合
血运重建
干细胞
再生(生物学)
祖细胞
细胞生物学
医学
病理
外科
生物
内科学
心肌梗塞
作者
Biao Cheng,Xiaobing Fu
标识
DOI:10.1177/15347346231210709
摘要
Wound healing is a complex and dynamic process involving a series of cellular and molecular events. Revascularization, the restoration of blood flow to ischemic or damaged tissue, is a key step in wound healing. Adequate vascularization has been recognized as a necessary factor for successful tissue regeneration. In the later stage of revascularization and tissue remodeling in wound healing, stem cells regulate other repair cells and matrix formation by influencing the maturation of blood vessels. The reductive oxidation (REDOX) state may be a key mechanism through stem/progenitor cells to influence endothelial cells to mature blood vessels and improve the quality of healing. Mitochondria may play an important role in this process.
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