Electron transfer-driven nanozymes integrated “colorimetric-photothermal” nanobody-immunosensing for tropomyosin inspection

We have generated a highly sensitive detection platform based on TM specific Nbs and nanozyme-mediated enhanced signaling. The versatile Nb-nanozyme detection platform integrates electron-transfer catalysis and photothermal transduction for dual-mode readout. The established method could offer a promising foundation and inspire further investigation on portable, low-cost point-of-care testing of food allergens and other biomolecular targets.