[Advances in frontier technologies and innovative applications for the prevention and control of hospital infections associated with multidrug-resistant bacteria].

Hospital-acquired infections (HAIs) significantly increase patient mortality and healthcare burden, with multidrug-resistant organisms (MDROs) exacerbating the challenge through diverse transmission routes, posing a global public health threat. Traditional control measures (e.g., hand hygiene, environmental disinfection, and antibiotic stewardship) remain central to HAI prevention but face technical and managerial limitations. Recent advances in novel technologies, including nanomaterials, phage therapy, and artificial intelligence, provide critical enhancements to existing control systems. This article systematically evaluates MDROs-related HAI control strategies and their clinical applications, proposing a future HAI prevention framework centered on technological precision, data integration, and dynamic adaptability.