MP09-15 CAN CLINICAL PROSTATE SCORE (CLIPS) BE USED AS A USEFUL ADJUNCT FOR PREDICTING SUCCESS IN MINIMAL INVASIVE SURGICAL THERAPY (MIST) OF THE PROSTATE?

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Epidemiology, Evaluation & Medical Non-surgical Therapy (MP09)1 May 2024MP09-15 CAN CLINICAL PROSTATE SCORE (CLIPS) BE USED AS A USEFUL ADJUNCT FOR PREDICTING SUCCESS IN MINIMAL INVASIVE SURGICAL THERAPY (MIST) OF THE PROSTATE? Gregory Pek, Terence Law, Wei Jin Chua, Edmund Chiong, David Consigliere, and Woon C. Tsang Gregory PekGregory Pek , Terence LawTerence Law , Wei Jin ChuaWei Jin Chua , Edmund ChiongEdmund Chiong , David ConsigliereDavid Consigliere , and Woon C. TsangWoon C. Tsang View All Author Informationhttps://doi.org/10.1097/01.JU.0001008920.55771.18.15AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: CLIPS is a novel method for predicting bladder outlet obstruction (BOO) without the need for invasive methods such as urodynamics studies.1 CLIPS was used clinically to measure voiding functions for patient going for MIST.2 Ito et al. proposed maximum flow rate (Qmax) and international prostate symptom score (IPSS) as favorable predictive factors to determine prostate surgery outcomes.3 Our aim was to correlate the effectiveness of CLIPS as a useful adjunct for patients going for MIST of the prostate. METHODS: 148 LUTS patients were recruited prospectively for MIST of the prostate (either prostate UroLift or transurethral ablation of prostate (REZUM)) between 2020 to 2022. They were reviewed at 3, 12 and 24 months with assessment of prostate volume (PV), IPSS, Quality of life (QoL) and international index of erectile function (IIEF) questionnaires and uroflow parameters (Qmax, voided volume (VV), post void residual (PVR)). Patients were stratified according to CLIPS; no BOO if 3*Qmax was greater than PV and BOO if 3*Qmax was less than PV. We also examined IPSS changes from baseline after prostate surgery. Analysis was done using student t-test comparing the non-obstructing and obstructing groups. RESULTS: 148 LUTS patients (mean age 64 years) were recruited. Table 1 showed patients stratified according to CLIPS and PV 40 cc as a cut-off. There were significant differences for Qmax and CLIPS at 3, 12 and 24 months (p<0.0001) between the 2 groups. VV was much better for patients with PV <40 cc and in those with no BOO. There was significant IPSS improvement using IPSS 16 as a cut-off between the 2 groups at 3 months (IPSS<16: -11.15±6.79 and 4.50±10.73, p<0.0001 vs IPSS >16: -8.23±9.95 and 3.83±9.24, p=0.00095), 12 months (IPSS <16: -11.12±6.08 and -0.40±2.97, p=0.0007 vs IPSS >16: -6.86±8.84 and 2.88±11.48, p=0.00111) and 24 months (IPSS <16: -6.79±9.31 and 0.71±3.55, p=0.0558 vs IPSS >16: -12.18±5.08 and 2.14±8.24, p=0.0003). Patients had IPSS improvement of 81.2% at 3 months, 85.5% at 12 months and 80.8% at 24 months if IPSS <16 respectively and worsening symptoms of 50% at 3 months, 23.1% at 12 months and 57.1% at 24 months if IPSS >16. CONCLUSIONS: CLIPS can be used to predict possible outcome of MIST especially using Qmax and changes in IPSS score. Prostate <40 cc and IPSS <16 have better surgical outcome compared to larger prostates and IPSS >16. A larger study would be needed to validate this. References: 1. Rosier et al. ICS 2022; 2. Tsang et al. AUA 2023; 3. Ito et al. European Urology Focus 2023. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e132 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Gregory Pek More articles by this author Terence Law More articles by this author Wei Jin Chua More articles by this author Edmund Chiong More articles by this author David Consigliere More articles by this author Woon C. Tsang More articles by this author Expand All Advertisement PDF downloadLoading ...