Detachable MOF‐Based Core/Shell Nanoreactor for Cancer Dual‐Starvation Therapy With Reversing Glucose and Glutamine Metabolisms

mediated by GOD. Last, the released GOD and BPTES collaboratively cut off the energy supply of tumors and induce significant mitochondrial damage and cell cycle arrest via simultaneous restriction of glycolysis and compensatory glutamine metabolism pathways, consequently realizing the remarkable triple negative breast cancer killing effect in vivo with good biosafety via the dual starvation therapy.