材料科学
纳米技术
生物相容性
相(物质)
表面改性
膜
生物分子
复合数
同种类的
制作
化学工程
化学
复合材料
工程类
有机化学
物理
病理
热力学
冶金
医学
替代医学
生物化学
作者
Yingchao Yang,Yunfei Ru,Tianyi Zhao,Mingjie Liu
出处
期刊:Chem
[Elsevier]
日期:2023-11-01
卷期号:9 (11): 3113-3137
被引量:5
标识
DOI:10.1016/j.chempr.2023.08.012
摘要
Summary
Phase separation in living organisms is essential for the execution of biological functions, for example, the formation of membrane-less organelles and the functionalization of extracellular matrix proteins. In synthetic soft matter, gels have similarities to biological tissues due to their wet/soft properties and good biocompatibility. However, conventional gels with homogeneous networks are mechanically intolerant and unstable in solvent, which restricts their applications in various fields. Inspired by protein phase transitions of cellular processes in organisms, micro-phase separation is introduced into gel networks and devolved a series of robust functionalities gel materials. In this review, the critical design criteria and fabrication strategies of gel materials with micro-phase separation are summarized. Then, the multiple functionalities of these materials are systemically reviewed, including surface engineering, mechanical properties, shape memory, and sensor properties. Furthermore, we explore the current challenges and prospects in bioinspired micro-phase-separated gel field.
科研通智能强力驱动
Strongly Powered by AbleSci AI