对映选择合成
烯丙基重排
铱
催化作用
化学
亲核细胞
组合化学
替代(逻辑)
取代反应
有机化学
计算机科学
程序设计语言
作者
Amit Singh Adhikari,Soumen Pandit,Ravi Kant,Nilanjana Majumdar
标识
DOI:10.1021/acscatal.3c00959
摘要
An efficient method for a highly regio- and enantioselective allylic substitution of vinylcyclopropanes using carboxylic acids as oxygen nucleophile via iridium catalysis has been developed. This represents a highly atom-economic approach for the synthesis of synthetically useful chiral building blocks in high yields. The practical utility of this method is demonstrated by the application of the products in useful transformations.
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