作者
Federico Piramide,Filippo Turri,Daniele Amparore,Giuseppe Fallara,Ruben De Groote,Sophie Knipper,Christoph Wuernschimmel,Carlo Andrea Bravi,E. Warren Lambert,Fabrizio Di Maida,Nikolaos Liakos,Francesco Pellegrino,Iulia Andraș,Alessandro Mastrorosa,Neeraja Tillu,Riccardo Mastroianni,Marco Paciotti,Mike Wenzel,Roberto Bianchi,Ettore Di Trapani,Marcio Covas Moschovas,Giorgio Gandaglia,Marco Moschini,Frederiek D’Hondt,Bernardo Rocco,Cristian Fiori,Antonio Galfano,Andrea Minervini,Giuseppe Simone,Alberto Briganti,O. De Cobelli,Richard Gastón,Francesco Montorsi,Alberto Breda,Peter Wiklund,Francesco Porpiglia,Alexandre Mottrie,Alessandro Larcher,Paolo Dell’Oglio
摘要
Multiple and heterogeneous techniques have been described for orthotopic neobladder (ONB) reconstruction after robot-assisted radical cystectomy. Nonetheless, a systematic assessment of all the available options is lacking. To provide the first comprehensive step-by-step description of all the available techniques for robotic intracorporeal ONB together with individual intraoperative, perioperative and functional outcomes based on a systematic review of the literature. We performed a systematic review of the literature, and MEDLINE/PubMed, Embase, Scopus, and Web of Science databases were searched to identify original articles describing different robotic intracorporeal ONB techniques and reporting intra- and perioperative outcomes. Studies were categorized according to ONB type, providing a synthesis of the current evidence. Video material was provided by experts in the field to illustrate the surgical technique of each intracorporeal ONB. Nine different ONB types were identified: Studer, Hautmann, Y shape, U shape, Bordeaux, Pyramid, Shell, Florence Robotic Intracorporeal Neobladder, and Padua Ileal Neobladder. Continuous and categorical variables are presented as mean ± standard deviation and as frequencies and proportions, respectively. Of 2587 studies identified, 19 met our inclusion criteria. No cohort studies or randomized control trials comparing different neobladder types are available. Available techniques for intracorporeal robotic ONB reconstruction have similar operative time, estimated blood loss, intraoperative complications, and length of stay. Major variability exists concerning postoperative complications and functional outcomes, likely related to reporting bias. Several techniques are described for intracorporeal ONB during robot-assisted radical cystectomy with comparable perioperative outcomes. We provide the first step-by-step surgical atlas for robot-assisted ONB reconstruction. Further comparative studies are needed to assess any advantage of one technique over others. Patients elected for radical cystectomy should be aware that multiple techniques for robotic orthotopic neobladder are available, but that current evidence does not favor one type over the others.