Objective To study the effect of Motreal cognitive assessment(MoCA)(Chinese version) in diagnosing the amnestic mild cognitive impairment.Methods A total of 61 persons were chosen from the outpatient section of Beijing Hospital(2009-05-2010-03),including 31 patients who meeting the criteria of MCI-Revised(MCI-R) and 30 normal controls(NC) for comparing the sensitivity and specificity of the mini-mental state examination(MMSE) and MoCA in diagnosing the aMCI and analysing the effect and characteristics of MoCA in diagnosing the aMCI.Results When using the cut off score of 26,the sensitivity of MMSE and MoCA are 9.68% and 87.10% separately,the specificity are 93.33% and 73.33%.Conclusions MoCA might play an important role in screening aMCI and the other cognitive impairments due to the better sensitivity of MoCA and its wide cover of multiple cognitive district.