Object To observe the analgesic and anti-inflammatory actions of Compound Nilentriol Tablets (CNT).Methods Hot-plate method for mice and tail flick method for rats were used to check pain threshold after administration with CNT,aspirin and araban respectively.Furthermore,the ankle swelling caused by carrageenin and the granuloma caused by cotton in pellet in rats were made to observe the anti-inflammatory effect of CNT.Results The dose depending analgesic and anti-inflammatory actions of CNT were demonstrated by analgesic and inflammatory models.Conclusion CNT has significant analgesic and anti-inflammatory effects.