医学
糖尿病性视网膜病变
分级(工程)
荧光血管造影
眼科
新生血管
血管造影
核医学
放射科
糖尿病
视网膜
内科学
工程类
内分泌学
土木工程
血管生成
作者
Hasenin Al-Khersan,Jonathan F. Russell,Thomas A. Lazzarini,Nathan L. Scott,John W. Hinkle,Nimesh A. Patel,Nicolas A. Yannuzzi,Benjamin J. Fowler,Rehan M. Hussain,Anita Barikian,Jayanth Sridhar,Stephen R. Russell,Luis J. Haddock,William E. Smiddy,Seenu M. Hariprasad,Yingying Shi,Liang Wang,William J. Feuer,Giovanni Gregori,Philip J. Rosenfeld
标识
DOI:10.1016/j.ajo.2020.11.020
摘要
We compared the ability of ophthalmologists to identify neovascularization (NV) in patients with proliferative diabetic retinopathy using swept-source optical coherence tomography angiography (SS-OCTA) and fluorescein angiography (FA).Retrospective study comparing diagnostic instruments.Eyes with proliferative diabetic retinopathy or severe nonproliferative diabetic retinopathy and a high suspicion of NV based on clinical examination were imaged using SS-OCTA and FA at the same visit. Two separate grading sets consisting of scrambled, anonymized SS-OCTA and FA images were created. The ground truth for presence of NV was established by consensus of 2 graders with OCTA experience who did not participate in the subsequent assessment of NV in this study. The 2 anonymized image sets were graded for presence or absence of NV by 12 other graders that included 2 residents, 6 vitreoretinal fellows, and 4 vitreoretinal attending physicians. The percentage of correct grading of NV using SS-OCTA and FA was assessed for each grader and across grader training levels.Forty-seven eyes from 24 patients were included in this study. Overall, the mean percentage of correct NV grading was 87.8% using SS-OCTA with B-scans and 86.2% using FA (P = .92). Assessing each grader individually, there was no statistically significant asymmetry in correct grading using SS-OCTA and FA.Ophthalmologists across training levels were able to identify diabetic NV with equal accuracy using SS-OCTA and FA. Based on these results, SS-OCTA may be an appropriate standalone modality for diagnosing diabetic NV.
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