刺激
反射
胃肠道
内分泌学
内科学
消化(炼金术)
迷走神经
假喂食
内分泌系统
品味
胃酸
生物
胃
医学
化学
神经科学
激素
色谱法
作者
S. A. Giduck,Rose M. Threatte,Morley R. Kare
标识
DOI:10.1093/jn/117.7.1191
摘要
Stimulation of the oral cavity immediately elicits salivation, gastric acid secretion and pancreatic exocrine and endocrine secretions that serve to prepare the alimentary canal for digestion, transport and utilization of ingested nutrients. Oropharyngeal-stimulated responses are reliably initiated by the taste and smell of food. These gastrointestinal reflexes, often referred to as anticipatory or cephalic phase responses, are mediated by the autonomic nervous system and are believed to be independent of the postabsorptive effects of ingested nutrients. A common pathway used by cephalic phase responses to trigger gastrointestinal secretions is the vagus. Several studies have also demonstrated that cephalic stimulation activates both the sympathetic and parasympathetic nervous systems and thus, many cephalic-metabolic reflexes may arise indirectly from more general physiological changes that accompany oropharyngeal stimulation. The present studies suggest that oral stimulation results in alterations in intestinal function. Specifically, oropharyngeal stimulation of conscious, unrestrained rats with sucrose increases the uptake of radioactive glucose from the small intestine into the hepatic portal blood.
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