昼夜节律
生物钟
生物
神经科学
细胞生物学
果蝇属(亚属)
分子钟
振荡基因
句号(音乐)
永恒的
节奏
细菌昼夜节律
内科学
遗传学
基因
物理
医学
声学
系统发育学
作者
Xitong Liang,Timothy E. Holy,Paul H. Taghert
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2016-02-26
卷期号:351 (6276): 976-981
被引量:150
标识
DOI:10.1126/science.aad3997
摘要
Layered versatility atop circadian clocks The circadian clock evolved to allow cells or organisms to anticipate changes in physiological requirements associated with Earth's 24-hour light/dark cycle. Some activities, however, need to occur out of phase with the core clock. Liang et al. imaged changes in intracellular concentration of Ca 2+ in populations of neurons in the fruit fly brain. Although the underlying clock was synchronous, the rhythms of Ca 2+ changes corresponded with distinct timing of activities associated with activity of the particular neuronal populations. Proper coordination of these distinct phases required expression of the neuropeptide pigment-dispersing factor and its receptor. Science , this issue p. 976
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