Samples of Zhike from 6 places were determined by Reversed-Phase High Performance Liquid Chro-matography (re-HPLC). The results showed that the content of naringin ranged from 12. 05 mg·g-1 to 59.80 mg·g-1.the content of hesperidin ranged from 0.29 mg·g-1 to 11. 63 mg·g-1,the content of sypephrine ranged from 0.21 mg·g-1 to 37. 22 mg·g-1.