In vitro Antibacterial Action of Extracts from Coptis Root

SummaryThe dilute alcohol extract of the coptis root has been demonstrated to have a definite and fairly high antibacterial action against a number of both Gram positive and Gram negative bacteria. Its lethal dose for albino rats has been found to be more than 250 mg per kg body weight.The author wishes to express his deep gratitude to Professor Samuel H. Zia for his constant advice and helpful criticisms during this investigation.