CTQ树
精神病
性虐待
精神分裂症(面向对象编程)
临床心理学
忽视
精神分裂症谱
医学
精神科
抗精神病药
身体虐待
心理学
毒物控制
伤害预防
家庭暴力
环境卫生
作者
N. Mørkved,Erik Johnsen,Rune A. Kroken,Inge Joa,Eirik Kjelby,Maria A. Rettenbacher,C.A. Bartz-Johannessen,E-M Løberg
标识
DOI:10.1016/j.psychres.2024.116169
摘要
Treatment with antipsychotics (APs) for schizophrenia spectrum disorders (SSDs) is generally effective, however, a significant proportion does not respond favorably. Childhood trauma (CT) subtypes (physical, sexual, and emotional abuse, physical and emotional neglect) could influence treatment effectiveness; however, research is scarce. Heterogeneity in AP response could be explained by differentiating by CT subtype. The present study was based on the Bergen-Stavanger-Trondheim-Innsbruck (BeSt InTro) study. CTQ-SF assessed CT subtypes in SSDs (n = 98). CT subtypes were examined in relation to psychosis symptoms measured by PANSS during one year of treatment with APs, by means of linear mixed effects (LME) models. Results were significant for CT subtypes, where increased levels of sexual abuse and physical neglect were associated with increased mean levels of psychosis symptoms throughout the course of treatment from baseline to 52 weeks. AP effectiveness may thus be influenced by CT subtype in SSDs. The results support clinical guidelines recommending a focus on assessment and treatment of trauma in SSDs.
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