血小板活化
血栓形成
血小板
化学
线粒体
细胞生物学
血小板聚集
内皮细胞活化
酶激活剂
医学
血小板因子4
生物化学
内科学
ALDH2
药理学
生物
血小板粘附
作者
Haoxuan Zhong,Maieryemu Waresi,Zhiyong Qi,Luning Zhou,Wei Zhang,Xiaolei Sun,Liping Han,Zhihan Chen,Wenting Zhou,Peng Zhang,Huajie Xu,Si Zhang,Hongyi Wu,Aijun Sun,Junbo Ge
摘要
The ALDH2 rs671 variant enhances collagen-induced platelet activation and thrombosis by impairing mitochondrial complex I assembly and function. NAD+ supplementation offers a promising strategy to mitigate thrombotic risk in individuals carrying this variant.
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(2025-6-4)
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