酒精性心肌病
医学
心力衰竭
心肌病
流行病学
心脏病学
心脏病
内科学
酒
糖尿病
酒精与健康
饮酒量
内分泌学
生物
生物化学
作者
Debar Rasoul,Ashwin Ajay,Abm Abdullah,Jean Mathew,Benjamin Lee Wei En,Knievel Mashida,Rajiv Sankaranarayanan
摘要
Alcohol is the most frequently consumed toxic substance in the world and remains a major global public health issue, with one in three adults consuming it worldwide. Alcohol use is a leading risk factor for disease, contributing to over 60 acute and chronic health conditions, with a particularly complex association with cardiovascular disease. Chronic excessive alcohol consumption is associated with a range of cardiac complications, including decreased myocardial contractility, hypertension, arrhythmias, MI and heart failure. However, low-level alcohol consumption is believed to have a protective effect against ischaemic heart disease and diabetes. In most cohort studies, small to moderate amounts of alcohol consumption have not been linked to heart failure, indicating a threshold effect of alcohol with individual (possibly genetic) predisposition rather than a continuous effect of exposure. This review article explores the potential benefits of alcohol on the heart, the association between alcohol use and alcoholic cardiomyopathy and the epidemiology, clinical correlates and management of alcoholic cardiomyopathy.
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