Knowledge exchange, despite its burgeoning presence in literature, often grapples with definitional ambiguities due to its conflation with other knowledge management terminologies. This paper endeavours to elucidate the nuances of knowledge exchange and demarcate its contextual landscapes in existing literature. A co-occurrence of keyword analysis was completed, where 65 keywords with a threshold of 50+ occurrences were analysed. Subsequent literature scrutiny unveiled three pivotal themes: knowledge exchange geared towards assimilating health and science knowledge, the synergy of knowledge among enterprises for innovation and development, and the transposition of research into actionable decision-making and policy formulation. Rooted in these themes, this research posits that knowledge exchange seamlessly dovetails myriad knowledge management processes, spanning creation to application. Notably, this study provides essential insights to differentiate knowledge exchange from other knowledge management terms, laying a foundational reference for future research and offering a valuable compilation of reported knowledge exchange mechanisms for practical testing.