医学
主动脉夹层
病理生理学
弹性蛋白
细胞外基质
生物标志物
炎症
内科学
疾病
病理
诊断生物标志物
基质金属蛋白酶
主动脉瘤
解剖(医学)
生物信息学
重症监护医学
放射科
主动脉
诊断准确性
生物
细胞生物学
生物化学
作者
Muhammad Ali Muzammil,Neeru Chaudhary,Syed Muhammad Abbas,Owais Ahmad,Aqsa Nasir,Eesha Baig,Fnu Fariha,Azra Khan Afridi,Sahil Zaveri
标识
DOI:10.1097/hpc.0000000000000355
摘要
Aortic dissection (AD) is a potentially fatal cardiovascular issue that needs to be diagnosed and treated very away. While early detection is essential for bettering patient outcomes, there are substantial obstacles with the diagnostic techniques used today. Promising pathways for improving AD prognosis evaluation and early detection are presented by recent developments in serum biomarkers. The most recent research on serum biomarkers for AD is reviewed here, with an emphasis on the prognostic and diagnostic utility of these indicators. A number of biomarkers, including as matrix metalloproteinases, soluble elastin fragments, smooth muscle myosin heavy chain, and D-dimer, have been identified as putative markers of AD. These indicators are indicative of multiple pathophysiological mechanisms associated with AD, including inflammation, extracellular matrix remodeling, and vascular damage. Research has indicated that they are useful in differentiating AD from other acute cardiovascular diseases, facilitating prompt diagnosis and risk assessment.
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