活性氧
抗氧化剂
氧化磷酸化
抗生素
微生物学
细菌
化学
氧化应激
细胞生物学
生物
生物化学
遗传学
作者
Jiajie Zhang,Shanliang Ye,Wei Yu
出处
期刊:Chinese journal of microbiology and immunology
日期:2019-02-28
卷期号:39 (2): 157-160
标识
DOI:10.3760/cma.j.issn.0254-5101.2019.02.014
摘要
Antibiotics can not only combine with specific targets, but also induce a cascade of reactive oxygen species (ROS) in bacteria. Antioxidant defense system plays an important role in scavenging ROS and repairing injury against oxidative stress. However, the mechanism of ROS accumulation in bacteria and the action of ROS are very complicated. Therefore, this paper reviewed the mechanisms of bacterial responding to oxidative stress in the existence of antibiotics. In addition, we analyzed the main problems lying in the current study and the issues needing further consideration.
Key words:
ROS; Oxidative stress; Antioxidant defense; Transcriptional regulation
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