Iridium-catalyzed sp3 C–H Alkylation of 3-Carbonyl-2-(alkylamino)pyridines with Alkenes

Iridium-catalyzed C–H alkylation of 3-carbonyl-2-(alkylamino)pyridines via secondary sp3 C–H activation adjacent to the nitrogen atom, with terminal alkenes proceeded to give the corresponding α-secondary amines in high yields. The reaction was efficiently catalyzed by a cationic iridium complex coordinated with 1,5-cyclooctadiene.